Eurotimes Articles

Cornea

Cornea Articles

While many investigators are focusing on modifications to the standard CXL technique, Jorge F Alio MD, PhD, Alfredo Vega-Estrada MD, MSc and colleagues at Vissum Corporacion Oftalmologica, Universidad Miguel Hernandez, Alicante, Spain, are developing a novel “lightfree” tissue engineering approach to reinforce the corneal tissue using carbon nanomaterials. Speaking during the Expert Meeting on the Surgical Management of Keratoconus, Dr Alio described the technology, presented outcomes of an initial preclinical study, and talked about the next steps for its development.

Acanthamoeba keratitis remains a rare condition and particularly in developing countries. However, the numbers of these infections have been rising significantly in the US and other industrialised nations, and as the populations in underdeveloped areas become more affluent, there is the potential for a geometric increase in cases, said Elmer Tu MD, speaking at Cornea Day during the 26th Asia-Pacific Association of Cataract & Refractive Surgeons meeting in Singapore.

Thinner lamellar endothelial grafts result in better visual outcomes sooner after surgery compared to thick lamellar grafts or penetrating keratoplasty (PKP), according to a study presented at the 2013 Congress of the European Society of Ophthalmology.

Femtosecond lasers are finding a diverse range of uses in keratoplasty procedures, although the expense of the instruments must be weighed against the relatively modest benefits, if any, that they provide in terms of visual outcomes, according to several presenters speaking at Femto 2013, an international meeting on anterior segment surgery.

A new collagen cross-linking technique (CXL) that uses iontophoresis to enhance penetration of riboflavin through epithelial tissue may enable patients to undergo the procedure without the need for epithelial debridement, said Francois Malecaze MD, CHU de Toulouse-Hopital Purpan, Toulouse, France, at Femto 2013, an international meeting on anterior segment surgery.

Advanced tissue typing techniques such as human leukocyte antigen (HLA) matching deserve greater attention as a potential means of increasing the survival of corneal grafts over the long term, according to John Armitage PhD, director of tissue banking at the University of Bristol, UK.

The growing popularity of posterior lamellar keratoplasty techniques in recent years has led to a significant reduction in the risk of graft rejection after corneal transplants, according to researchers at the 2013 Congress of the European Society of Ophthalmology (SOE).

A new technique for manipulating endothelial grafts onto the posterior corneal stroma of eyes undergoing Descemet’s membrane endothelial keratoplasty (DMEK) can speed up the surgical procedure and reduce the graft detachment and partial detachment rate, said José Güell MD, Autonomous University of Barcelona, Barcelona, Spain.

Biosynthetic corneal implants made of fish scale- derived collagen may in the near future provide a potentially safe and effective alternative to the implantation of human tissue to help address the current donor cornea shortage worldwide, report researchers.

Biosynthetic corneal implants could offer a safe and effective alternative to the implantation of human tissue to help address the current donor cornea shortage, suggests research presented at the 2013 Congress of the European Society of Ophthalmology meeting. “Recombinant human collagen has now been successfully tested as immune compatible implants in humans. The biomaterials can be used to induce endogenous host stem cells to affect regeneration or to deliver exogenous stem cells.

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